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Cannabis & Schizophrenia

Cannabis use has been associated with increased risk of psychiatric disorders. A 15-year study of 50,465 male subjects reported that those who had tried cannabis by age 18 years were 2·4 times more likely to be diagnosed with schizophrenia than those who had not.

Risk increased with the frequency of cannabis use and remained significant.Those who had used cannabis ten or more times by 18 years of age were 2·3 times more likely to be diagnosed with schizophrenia than those who had not.

They estimated that 13% of schizophrenia cases could be averted if cannabis use was prevented.

Source: Review | www.thelancet.com | Vol 374 October 17, 2009
Adverse health effects of non-medical cannabis Use by Wayne Hall, Louisa Degenhardt

For over two decades, cannabis, commonly known as marijuana, has been the most widely used illicit drug by young people in high-income countries, and has recently become popular on a global scale. Epidemiological research during the past 10 years suggests that regular use of cannabis during adolescence and into adulthood can have adverse effects. Epidemiological, clinical, and laboratory studies have established an association between cannabis use and adverse outcomes. We focus on adverse health effects of greatest potential public health interest—that is, those that are most likely to occur and to affect a large number of cannabis users. The most probable adverse effects include a dependence syndrome, increased risk of motor vehicle crashes, impaired respiratory function, cardiovascular disease, and adverse effects of regular use on adolescent psychosocial development and mental health.

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